ILBJH Cases

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Enhance your knowledge in Rheumatology

A 55-year-old patient presents with mid-back pain persisting for three months. After thorough examination and testing, the patient is diagnosed with multiple myeloma.

Multiple myeloma accounts for one of the 'M's in the popular mnemonic for lucent bone lesions FEGNOMASHIC.

A whole body MRI technique may be deployed. MRI is more sensitive in detecting multiple lesions compared to the standard plain film skeletal survey and CT MRI revealed Multifocal abnormal bone marrow signal intensity is seen involving the spine mainly at D6, D7, D8 and D11 vertebra with reduction of the vertebral heights due to axial compression fracture and significant post contrast enhancement, no paravertebral mass or fluid collection.

Which of the following MRI findings is most consistent with this diagnosis?

Herniated intervertebral disc

Osteoporotic vertebral compression fractures

Diffuse marrow infiltration with low signal intensity on T1-weighted images

Spinal cord edema

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